Almost every cosmonaut suffers from the so called "space disease". This disease is characterized by headaches, nausea.
In conditions of zero gravity, liquids move up. That's why the nose is permanently blocked, and the face becomes "pumped-up". Cosmonauts' height increases in space.
In the result of an experiment, when a pregnant rat was sent to space, it was determined that the development of the child in space is almost impossible.
A very good point is that in space the cosmonauts don't snore. It seems that women should start living with their snoring husbands in space
A negative point is that you see 16 sunrises in one day, which gives a negative effect to your body.